|
KMID : 1100620190060030250
|
|
Clinical and Experimental Emergency Medicine
2019 Volume.6 No. 3 p.250 ~ p.256
|
|
|
Worsened survival in the head-up tilt position cardiopulmonary resuscitation in a porcine cardiac arrest model
|
|
Park Yong-Joo
Hong Ki-Jeong
Shin Sang-Do
Kim Tae-Yun
Ro Young-Sun
Song Kyoung-Jun
Ryu Hyun-Ho
|
|
|
Abstract
|
|
|
Objective: Head elevation at an angle of 30° during cardiopulmonary resuscitation (CPR) was hemodynamically beneficial compared to supine position in a previous porcine cardiac arrest experimental study. However, survival benefit of head-up elevation during CPR has not been clarified. This study aimed to assess the effect of head-up tilt position during CPR on 24-hour survival in a porcine cardiac arrest experimental model.
Methods: This was a randomized experimental trial using female farm pigs (n=18, 42±3 kg) sedated, intubated, and paralyzed on a tilting surgical table. After surgical preparation, 15 minutes of untreated ventricular fibrillation was induced. Then, 6 minutes of basic life support was performed in a position randomly assigned to either head-up tilt at 30° or supine with a mechanical CPR device, LUCAS-2, and an impedance threshold device, followed by 20 minutes of advanced cardiac life support in the same position. Primary outcome was 24-hour survival, analyzed by Fisher exact test.
Results: In the 8 pigs from the head-up tilt position group, one showed return of spontaneous circulation (ROSC); all eight pigs expired within 24 hours. In the eight pigs from the supine position group, six had the ROSC; six pigs survived for 24 hours and two expired. The head-up position group showed lower 24-hour survival rate and lower ROSC rate than supine position group (P<0.01).
Conclusion: The use of head-up tilt position with 30 degrees during CPR showed lower 24-hour survival than the supine position.
|
|
|
KEYWORD
|
|
|
Heart arrest, Cardiopulmonary resuscitation, Animal experimentation
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
 
|
|